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Mechanical Strain Stabilizes Reconstituted Collagen Fibrils against Enzymatic Degradation by Mammalian Collagenase Matrix Metalloproteinase 8 (MMP-8)

BACKGROUND: Collagen, a triple-helical, self-organizing protein, is the predominant structural protein in mammals. It is found in bone, ligament, tendon, cartilage, intervertebral disc, skin, blood vessel, and cornea. We have recently postulated that fibrillar collagens (and their complementary enzy...

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Hlavní autoři: Flynn, Brendan P., Bhole, Amit P., Saeidi, Nima, Liles, Melody, DiMarzio, Charles A., Ruberti, Jeffrey W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925882/
https://ncbi.nlm.nih.gov/pubmed/20808784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012337
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