Predictive Models for Maximum Recommended Therapeutic Dose of Antiretroviral Drugs

A novel method for predicting maximum recommended therapeutic dose (MRTD) is presented using quantitative structure property relationships (QSPRs) and artificial neural networks (ANNs). MRTD data of 31 structurally diverse Antiretroviral drugs (ARVs) were collected from FDA MRTD Database or package...

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Detalhes bibliográficos
Main Authors: Branham, Michael Lee, Ross, Edward A., Govender, Thirumala
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299291/
https://ncbi.nlm.nih.gov/pubmed/22481974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/469769
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