Predictive Models for Maximum Recommended Therapeutic Dose of Antiretroviral Drugs

A novel method for predicting maximum recommended therapeutic dose (MRTD) is presented using quantitative structure property relationships (QSPRs) and artificial neural networks (ANNs). MRTD data of 31 structurally diverse Antiretroviral drugs (ARVs) were collected from FDA MRTD Database or package...

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Autors principals: Branham, Michael Lee, Ross, Edward A., Govender, Thirumala
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299291/
https://ncbi.nlm.nih.gov/pubmed/22481974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/469769
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