Predictive Models for Maximum Recommended Therapeutic Dose of Antiretroviral Drugs

A novel method for predicting maximum recommended therapeutic dose (MRTD) is presented using quantitative structure property relationships (QSPRs) and artificial neural networks (ANNs). MRTD data of 31 structurally diverse Antiretroviral drugs (ARVs) were collected from FDA MRTD Database or package...

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Hlavní autoři: Branham, Michael Lee, Ross, Edward A., Govender, Thirumala
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2012
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299291/
https://ncbi.nlm.nih.gov/pubmed/22481974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/469769
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