A novel targeted system to deliver chemotherapeutic drugs to EphA2-expressing cancer cells

The efficacy of anti-cancer drugs is often limited by their systemic toxicities and adverse side effects. We report that the EphA2 receptor is over-expressed preferentially in several human cancer cell lines compared to normal tissues and that an EphA2 targeting peptide (YSAYPDSVPMMS) can be effecti...

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Библиографические подробности
Главные авторы: Wang, Si, Placzek, William J., Stebbins, John L., Mitra, Sayantan, Noberini, Roberta, Koolpe, Mitchell, Zhang, Ziming, Dahl, Russell, Pasquale, Elena B., Pellecchia, Maurizio
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299084/
https://ncbi.nlm.nih.gov/pubmed/22329578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm201743s
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