Shikonin extracted from medicinal Chinese herbs exerts anti-inflammatory effect via proteasome inhibition

Shikonin, extracted from medicinal Chinese herb (Lithospermum erythrorhizo), was reported to exert anti-inflammatory and anti-cancer effects both in vitro and in vivo. We have found that proteasome was a molecular target of shikonin in tumor cells, but whether shikonin targets macrophage proteasome...

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Hlavní autoři: Lu, Li, Qin, Aiping, Huang, Hongbiao, Zhou, Ping, Zhang, Chuanyin, Liu, Ningning, Li, Shujue, Wen, Guanmei, Zhang, Change, Dong, Weihua, Wang, Xuejun, Dou, Q. Ping, Liu, Jinbao
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299007/
https://ncbi.nlm.nih.gov/pubmed/21392503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2011.02.043
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