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The conserved translocase Tim17 prevents mitochondrial DNA loss
Maintenance of an intact mitochondrial genome is essential for oxidative phosphorylation in all eukaryotes. Depletion of mitochondrial genome copy number can have severe pathological consequences due to loss of respiratory capacity. In Saccharomyces cerevisiae, several bifunctional metabolic enzymes...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3298863/ https://ncbi.nlm.nih.gov/pubmed/18826960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn313 |
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