The conserved translocase Tim17 prevents mitochondrial DNA loss

Maintenance of an intact mitochondrial genome is essential for oxidative phosphorylation in all eukaryotes. Depletion of mitochondrial genome copy number can have severe pathological consequences due to loss of respiratory capacity. In Saccharomyces cerevisiae, several bifunctional metabolic enzymes...

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Autors principals: Iacovino, Michelina, Granycome, Caroline, Sembongi, Hiroshi, Bokori-Brown, Monika, Butow, Ronald A., Holt, Ian J., Bateman, Joseph M.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2009
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3298863/
https://ncbi.nlm.nih.gov/pubmed/18826960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn313
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