Role of Tim17 in coupling the import motor to the translocation channel of the mitochondrial presequence translocase

The majority of mitochondrial proteins use N-terminal presequences for targeting to mitochondria and are translocated by the presequence translocase. During translocation, proteins, threaded through the channel in the inner membrane, are handed over to the import motor at the matrix face. Tim17 is a...

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Vydáno v:eLife
Hlavní autoři: Demishtein-Zohary, Keren, Günsel, Umut, Marom, Milit, Banerjee, Rupa, Neupert, Walter, Azem, Abdussalam, Mokranjac, Dejana
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2017
Témata:
Biochemistry
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308891/
https://ncbi.nlm.nih.gov/pubmed/28165323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.22696
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