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A mutagenesis analysis of Tim50, the major receptor of the TIM23 complex, identifies regions that affect its interaction with Tim23

Maintenance of the mitochondrial proteome depends on import of newly made proteins from the cytosol. More than half of mitochondrial proteins are made as precursor proteins with N-terminal extensions called presequences and use the TIM23 complex for translocation into the matrix, the inner mitochond...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Dayan, Dana, Bandel, May, Günsel, Umut, Nussbaum, Inbal, Prag, Gali, Mokranjac, Dejana, Neupert, Walter, Azem, Abdussalam
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375917/
https://ncbi.nlm.nih.gov/pubmed/30765764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-38353-1
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