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Combined treatment of Aβ immunization with statin in a mouse model of Alzheimer’s disease
We evaluated the therapeutic efficacy of combined treatment of Aβ-immunization with simvastatin in an Alzheimer mouse model at age 22 months. DNA prime-adenovirus boost immunization induced modest anti-Aβ titers and simvastatin increased the seropositive rate. Aβ-KLH was additionally administered to...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3298635/ https://ncbi.nlm.nih.gov/pubmed/22326143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2012.01.008 |
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