Deregulation of apoptosis-related genes is associated with PRV1 overexpression and JAK2 V617F allele burden in Essential Thrombocythemia and Myelofibrosis

BACKGROUND: Essential Thrombocythemia (ET) and Primary Myelofibrosis (PMF) are Chronic Myeloproliferative Neoplasms (MPN) characterized by clonal myeloproliferation/myeloaccumulation without cell maturation impairment. The JAK2 V617F mutation and PRV1 gene overexpression may contribute to MPN physio...

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Main Authors: Tognon, Raquel, Gasparotto, Elainy PL, Neves, Renata P, Nunes, Natália S, Ferreira, Aline F, Palma, Patrícia VB, Kashima, Simone, Covas, Dimas T, Santana, Mary, Souto, Elizabeth X, Zanichelli, Maria Aparecida, Simões, Belinda P, de Souza, Ana Maria, Castro, Fabíola A
格式: Artigo
語言:Inglês
出版: BioMed Central 2012
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3298534/
https://ncbi.nlm.nih.gov/pubmed/22300941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-5-2
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