Cytogenetics, JAK2 and MPL mutations in polycythemia vera, primary myelofibrosis and essential thrombocythemia

BACKGROUND: The detection of molecular and cytogenetic alterations is important for the diagnosis, prognosis and classification of myeloproliferative neoplasms. OBJECTIVES: The aim of this study was to detect the following mutations: JAK2 V617F, JAK2 exon 12 and MPL W515K/L, besides chromosomal abno...

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Detalhes bibliográficos
Main Authors: dos Santos, Leonardo Caires, Ribeiro, Juliana Corrêa da Costa, Silva, Neusa Pereira, Cerutti, Janete, da Silva, Maria Regina Regis, Chauffaille, Maria de Lourdes Lopes Ferrari
Formato: Artigo
Idioma:Inglês
Publicado em: Associação Brasileira de Hematologia e Hemoterapia 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3459377/
https://ncbi.nlm.nih.gov/pubmed/23049357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5581/1516-8484.20110116
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