Tumor necrosis factor-alpha inhibits expression of pulmonary surfactant protein.

Tumor necrosis factor-alpha (TNF-alpha) decreased the expression of pulmonary surfactant proteins SP-A and SP-B in human pulmonary adenocarcinoma cell lines. The effect of TNF alpha on SP-A content and mRNA in the pulmonary adenocarcinoma cell line, H441-4, was concentration and time dependent. TNF...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Wispé, J R, Clark, J C, Warner, B B, Fajardo, D, Hull, W E, Holtzman, R B, Whitsett, J A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329831/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2123888/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114929
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