Tumor necrosis factor-alpha inhibits expression of pulmonary surfactant protein.

Tumor necrosis factor-alpha (TNF-alpha) decreased the expression of pulmonary surfactant proteins SP-A and SP-B in human pulmonary adenocarcinoma cell lines. The effect of TNF alpha on SP-A content and mRNA in the pulmonary adenocarcinoma cell line, H441-4, was concentration and time dependent. TNF...

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Detalles Bibliográficos
Main Authors: Wispé, J R, Clark, J C, Warner, B B, Fajardo, D, Hull, W E, Holtzman, R B, Whitsett, J A
Formato: Artigo
Idioma:Inglês
Publicado: 1990
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC329831/
https://ncbi.nlm.nih.gov/pubmed/2123888
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