Tumor necrosis factor-alpha mediates changes in tissue protein turnover in a rat cancer cachexia model.

Rats bearing the Yoshida AH-130 ascites hepatoma showed enhanced fractional rates of protein degradation in gastrocnemius muscle, heart, and liver, while fractional synthesis rates were similar to those in non-tumor bearing rats. This hypercatabolic pattern was associated with marked perturbations o...

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Main Authors: Costelli, P, Carbó, N, Tessitore, L, Bagby, G J, Lopez-Soriano, F J, Argilés, J M, Baccino, F M
Format: Artigo
Jezik:Inglês
Izdano: 1993
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC288478/
https://ncbi.nlm.nih.gov/pubmed/8254032
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