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Stereoselective Synthesis of cis-2,5-Disubstituted Pyrrolidines via Wacker-Type Aerobic Oxidative Cyclization of Alkenes with (t)Bu-Sulfinamide Nucleophiles

[Image: see text] Palladium(II)-catalyzed aerobic oxidative cyclization of alkenes with tethered tert-butanesulfinamides furnishes enantiopure 2,5-disubstituted pyrrolidines, originating from readily available and easily diversified starting materials. These reactions are the first reported examples...

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Detalhes bibliográficos
Main Authors: Redford, Joanne E., McDonald, Richard I., Rigsby, Matthew L., Wiensch, Joshua D., Stahl, Shannon S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3298084/
https://ncbi.nlm.nih.gov/pubmed/22352383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol3000519
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