Effects of a novel cholecystokinin (CCK) receptor antagonist, MK-329, on gallbladder contraction and gastric emptying in humans. Implications for the physiology of CCK.

To explore the physiology of cholecystokinin (CCK) in humans, we investigated the effect on gallbladder contraction and gastric emptying of a recently developed CCK receptor antagonist, MK-329. In a double-blind, four-period crossover study eight subjects received single doses of 0.5, 2, or 10 mg MK...

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Εκδόθηκε σε:	J Clin Invest
Κύριοι συγγραφείς:	Liddle, R A, Gertz, B J, Kanayama, S, Beccaria, L, Coker, L D, Turnbull, T A, Morita, E T
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	American Society for Clinical Investigation 1989
Θέματα:	Research Article
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329781/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2794058/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114288
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