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Effects of a novel cholecystokinin (CCK) receptor antagonist, MK-329, on gallbladder contraction and gastric emptying in humans. Implications for the physiology of CCK.

To explore the physiology of cholecystokinin (CCK) in humans, we investigated the effect on gallbladder contraction and gastric emptying of a recently developed CCK receptor antagonist, MK-329. In a double-blind, four-period crossover study eight subjects received single doses of 0.5, 2, or 10 mg MK...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Liddle, R A, Gertz, B J, Kanayama, S, Beccaria, L, Coker, L D, Turnbull, T A, Morita, E T
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329781/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2794058/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114288
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