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Effects of a novel cholecystokinin (CCK) receptor antagonist, MK-329, on gallbladder contraction and gastric emptying in humans. Implications for the physiology of CCK.

To explore the physiology of cholecystokinin (CCK) in humans, we investigated the effect on gallbladder contraction and gastric emptying of a recently developed CCK receptor antagonist, MK-329. In a double-blind, four-period crossover study eight subjects received single doses of 0.5, 2, or 10 mg MK...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Liddle, R A, Gertz, B J, Kanayama, S, Beccaria, L, Coker, L D, Turnbull, T A, Morita, E T
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1989
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329781/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2794058/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114288
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