Effects of a novel cholecystokinin (CCK) receptor antagonist, MK-329, on gallbladder contraction and gastric emptying in humans. Implications for the physiology of CCK.

To explore the physiology of cholecystokinin (CCK) in humans, we investigated the effect on gallbladder contraction and gastric emptying of a recently developed CCK receptor antagonist, MK-329. In a double-blind, four-period crossover study eight subjects received single doses of 0.5, 2, or 10 mg MK...

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Detalles Bibliográficos

Publicado en:	J Clin Invest
Principais autores:	Liddle, R A, Gertz, B J, Kanayama, S, Beccaria, L, Coker, L D, Turnbull, T A, Morita, E T
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Clinical Investigation 1989
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329781/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2794058/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114288
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