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Modeling the Binding of Three Toxins to the Voltage-Gated Potassium Channel (Kv1.3)
The conduction properties of the voltage-gated potassium channel Kv1.3 and its modes of interaction with several polypeptide venoms are examined using Brownian dynamics simulations and molecular dynamics calculations. Employing an open-state homology model of Kv1.3, we first determine current-voltag...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Biophysical Society
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3297799/ https://ncbi.nlm.nih.gov/pubmed/22261053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.10.029 |
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