Pulmonary deposition and clearance of aerosolized alpha-1-proteinase inhibitor administered to dogs and to sheep.

Augmentation of lung antiprotease levels may be an important therapeutic intervention in the prevention of pulmonary emphysema. We have administered aerosols of plasma-derived human alpha 1 proteinase inhibitor (A1PI) to the lungs of dogs and sheep to investigate (a) delivery of the protein to the d...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Smith, R M, Traber, L D, Traber, D L, Spragg, R G
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1989
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329771/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2794051/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114278
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