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Pulmonary deposition and clearance of aerosolized alpha-1-proteinase inhibitor administered to dogs and to sheep.

Augmentation of lung antiprotease levels may be an important therapeutic intervention in the prevention of pulmonary emphysema. We have administered aerosols of plasma-derived human alpha 1 proteinase inhibitor (A1PI) to the lungs of dogs and sheep to investigate (a) delivery of the protein to the d...

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Bibliografiset tiedot
Julkaisussa:J Clin Invest
Päätekijät: Smith, R M, Traber, L D, Traber, D L, Spragg, R G
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 1989
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329771/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2794051/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114278
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