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A novel mutation in STK11 gene is associated with Peutz-Jeghers Syndrome in Chinese patients

BACKGROUND: Peutz-Jeghers syndrome (PJS) is caused by mutations in the tumor suppressor gene, STK11, and is characterized by gastrointestinal hamartomas, melanin spots on the lips, and an increased risk of developing cancer. METHODS: Blood samples were collected from two unrelated Chinese PJS famili...

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Main Authors: Wang, Zhiqing, Chen, Yulan, Wu, Baoping, Zheng, Haoxuan, He, Jiman, Jiang, Bo
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297525/
https://ncbi.nlm.nih.gov/pubmed/22168747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-12-161
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