Yellow fever 17D-vectored vaccines expressing Lassa virus GP1 and GP2 glycoproteins provide protection against fatal disease in guinea pigs

Yellow Fever (YF) and Lassa Fever (LF) are two prevalent hemorrhagic fevers co-circulating in West Africa and responsible for thousands of deaths annually. The YF vaccine 17D has been used as a vector for the Lassa virus glycoprotein precursor (LASV-GPC) or their subunits, GP1 (attachment glycoprote...

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Main Authors: Jiang, Xiaohong, Dalebout, Tim J., Bredenbeek, Peter J., Carrion, Ricardo, Brasky, Kathleen, Patterson, Jean, Goicochea, Marco, Bryant, Joseph, Salvato, Maria S., Lukashevich, Igor S.
格式: Artigo
語言:Inglês
出版: 2010
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297484/
https://ncbi.nlm.nih.gov/pubmed/21145373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.11.079
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