A Live Attenuated Vaccine for Lassa Fever Made by Reassortment of Lassa and Mopeia Viruses

Lassa virus (LASV) and Mopeia virus (MOPV) are closely related Old World arenaviruses that can exchange genomic segments (reassort) during coinfection. Clone ML29, selected from a library of MOPV/LASV (MOP/LAS) reassortants, encodes the major antigens (nucleocapsid and glycoprotein) of LASV and the...

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Detalhes bibliográficos
Main Authors: Lukashevich, Igor S., Patterson, Jean, Carrion, Ricardo, Moshkoff, Dmitry, Ticer, Anysha, Zapata, Juan, Brasky, Kathleen, Geiger, Robert, Hubbard, Gene B., Bryant, Joseph, Salvato, Maria S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280243/
https://ncbi.nlm.nih.gov/pubmed/16254329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.22.13934-13942.2005
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