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A ML29 Reassortant Virus Protects Guinea Pigs Against a Distantly-Related Nigerian Strain of Lassa Virus and can Provide Sterilizing Immunity
Lassa virus (LASV) is responsible for the deaths of thousands of people in West Africa annually. Genetic diversity among LASV strains is the highest among the Arenaviridae and represents a great challenge for vaccine development. Guinea pigs vaccinated with a ML29 reassortant vaccine experienced ste...
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Autori principali: | , , , , , , , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
2007
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1892204/ https://ncbi.nlm.nih.gov/pubmed/17360080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2007.02.038 |
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