A ML29 Reassortant Virus Protects Guinea Pigs Against a Distantly-Related Nigerian Strain of Lassa Virus and can Provide Sterilizing Immunity

Lassa virus (LASV) is responsible for the deaths of thousands of people in West Africa annually. Genetic diversity among LASV strains is the highest among the Arenaviridae and represents a great challenge for vaccine development. Guinea pigs vaccinated with a ML29 reassortant vaccine experienced ste...

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Main Authors: Carrion, Ricardo, Patterson, Jean L., Johnson, Curtis, Gonzales, Monica, Moreira, Carmen R., Ticer, Anysha, Brasky, Kathleen, Hubbard, Gene B., Moshkoff, Dmitry, Zapata, Juan, Salvato, Maria S., Lukashevich, Igor S.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892204/
https://ncbi.nlm.nih.gov/pubmed/17360080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2007.02.038
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