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Variable DNA Methylation Is Associated with Chronic Obstructive Pulmonary Disease and Lung Function

Rationale: Chronic obstructive pulmonary disease (COPD) is associated with local (lung) and systemic (blood) inflammation and manifestations. DNA methylation is an important regulator of gene transcription, and global and specific gene methylation marks may vary with cigarette smoke exposure. Object...

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Détails bibliographiques
Auteurs principaux: Qiu, Weiliang, Baccarelli, Andrea, Carey, Vincent J., Boutaoui, Nadia, Bacherman, Helene, Klanderman, Barbara, Rennard, Stephen, Agusti, Alvar, Anderson, Wayne, Lomas, David A., DeMeo, Dawn L.
Format: Artigo
Langue:Inglês
Publié: American Thoracic Society 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297093/
https://ncbi.nlm.nih.gov/pubmed/22161163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201108-1382OC
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