Smoking-Associated Site-Specific Differential Methylation in Buccal Mucosa in the COPDGene Study

DNA methylation is a complex, tissue-specific phenomenon that can reflect both endogenous factors and exogenous exposures. Buccal brushings represent an easily accessible source of DNA, which may be an appropriate surrogate tissue in the study of environmental exposures and chronic respiratory disea...

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Veröffentlicht in:Am J Respir Cell Mol Biol
Hauptverfasser: Wan, Emily S., Qiu, Weiliang, Carey, Vincent J., Morrow, Jarrett, Bacherman, Helene, Foreman, Marilyn G., Hokanson, John E., Bowler, Russell P., Crapo, James D., DeMeo, Dawn L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2015
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4566042/
https://ncbi.nlm.nih.gov/pubmed/25517428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2014-0103OC
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