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Glycosylation of α-amino acids by sugar acetate donors with InBr(3). Minimally competent Lewis acids

A simplified method for the preparation of Fmoc-serine and Fmoc-threonine glycosides for use in O-linked glycopeptide synthesis is described. Lewis acids promote glycoside formation, but also promote undesired reactions of the glycoside products. Use of “minimally competent” Lewis acids such as InBr...

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Detalhes bibliográficos
Main Authors: Lefever, Mark R., Szabò, Lajos Z., Anglin, Bobbi, Ferracane, Michael, Hogan, Joanna, Cooney, Lauren, Polt, Robin
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296895/
https://ncbi.nlm.nih.gov/pubmed/22342206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2012.01.008
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