SPECT/CT Imaging of hNIS -Expression after Intravenous Delivery of an Oncolytic Adenovirus and (131)I

Oncolytic adenoviruses can be engineered for better tumor selectivity, gene delivery and be armed for imaging and concentrating radionuclides into tumors for synergistic oncolysis. We constructed Ad5/3-hTERT-hNIS where replication is controlled by hTERT-promoter. Ad5/3-hTERT-hNIS expresses hNIS for...

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Detalhes bibliográficos
Main Authors: Rajecki, Maria, Sarparanta, Mirkka, Hakkarainen, Tanja, Tenhunen, Mikko, Diaconu, Iulia, Kuhmonen, Venla, Kairemo, Kalevi, Kanerva, Anna, Airaksinen, Anu J., Hemminki, Akseli
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296755/
https://ncbi.nlm.nih.gov/pubmed/22412937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032871
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