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Embryonic Stem Cell-Derived Factors Inhibit T Effector Activation and Induce T Regulatory Cells by Suppressing PKC-θ Activation

Embryonic stem cells (ESCs) possess immune privileged properties and have the capacity to modulate immune activation. However, the mechanisms by which ESCs inhibit immune activation remain mostly unknown. We have previously shown that ESC-derived factors block dendritic cell maturation, thereby indi...

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Bibliografiske detaljer
Main Authors: Mohib, Kanishka, AlKhamees, Bodour, Zein, Haggag S., Allan, David, Wang, Lisheng
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296708/
https://ncbi.nlm.nih.gov/pubmed/22412871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032420
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