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Embryonic Stem Cell-Derived Factors Inhibit T Effector Activation and Induce T Regulatory Cells by Suppressing PKC-θ Activation

Embryonic stem cells (ESCs) possess immune privileged properties and have the capacity to modulate immune activation. However, the mechanisms by which ESCs inhibit immune activation remain mostly unknown. We have previously shown that ESC-derived factors block dendritic cell maturation, thereby indi...

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Autors principals: Mohib, Kanishka, AlKhamees, Bodour, Zein, Haggag S., Allan, David, Wang, Lisheng
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296708/
https://ncbi.nlm.nih.gov/pubmed/22412871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032420
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