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Embryonic Stem Cell-Derived Factors Inhibit T Effector Activation and Induce T Regulatory Cells by Suppressing PKC-θ Activation

Embryonic stem cells (ESCs) possess immune privileged properties and have the capacity to modulate immune activation. However, the mechanisms by which ESCs inhibit immune activation remain mostly unknown. We have previously shown that ESC-derived factors block dendritic cell maturation, thereby indi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mohib, Kanishka, AlKhamees, Bodour, Zein, Haggag S., Allan, David, Wang, Lisheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296708/
https://ncbi.nlm.nih.gov/pubmed/22412871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032420
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