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Glucocorticosteroids Differentially Regulate MMP-9 and Neutrophil Elastase in COPD

BACKGROUND: Chronic Obstructive Pulmonary Disease (COPD) is currently the fifth leading cause of death worldwide. Neutrophilic inflammation is prominent, worsened during infective exacerbations and is refractory to glucocorticosteroids (GCs). Deregulated neutrophilic inflammation can cause excessive...

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Detalhes bibliográficos
Main Authors: Vlahos, Ross, Wark, Peter A. B., Anderson, Gary P., Bozinovski, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296684/
https://ncbi.nlm.nih.gov/pubmed/22413009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033277
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