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Glucocorticosteroids Differentially Regulate MMP-9 and Neutrophil Elastase in COPD

BACKGROUND: Chronic Obstructive Pulmonary Disease (COPD) is currently the fifth leading cause of death worldwide. Neutrophilic inflammation is prominent, worsened during infective exacerbations and is refractory to glucocorticosteroids (GCs). Deregulated neutrophilic inflammation can cause excessive...

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Detalles Bibliográficos
Autores principales: Vlahos, Ross, Wark, Peter A. B., Anderson, Gary P., Bozinovski, Steven
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296684/
https://ncbi.nlm.nih.gov/pubmed/22413009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033277
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