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Glucocorticosteroids Differentially Regulate MMP-9 and Neutrophil Elastase in COPD

BACKGROUND: Chronic Obstructive Pulmonary Disease (COPD) is currently the fifth leading cause of death worldwide. Neutrophilic inflammation is prominent, worsened during infective exacerbations and is refractory to glucocorticosteroids (GCs). Deregulated neutrophilic inflammation can cause excessive...

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Hlavní autoři: Vlahos, Ross, Wark, Peter A. B., Anderson, Gary P., Bozinovski, Steven
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296684/
https://ncbi.nlm.nih.gov/pubmed/22413009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033277
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