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Serum amyloid A overrides T(reg) anergy via monocyte-dependent and T(reg)-intrinsic, SOCS3-associated pathways

The acute phase protein serum amyloid A (SAA) has been well characterized as an indicator of inflammation. Nevertheless, its functions in pro versus anti-inflammatory processes remain obscure. Here we provide unexpected evidences that SAA induces the proliferation of the tolerogenic subset of regula...

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Bibliografische gegevens
Hoofdauteurs: Nguyen, Khoa D., Macaubas, Claudia, Nadeau, Kari C., Truong, Phi, Yoon, Taejin, Lee, Tzielan, Park, Jane L., Mellins, Elizabeth D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Hematology 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296631/
https://ncbi.nlm.nih.gov/pubmed/21325601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-11-318832
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