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Bistability in feedback circuits as a byproduct of evolution of evolvability
Noisy bistable dynamics in gene regulation can underlie stochastic switching and is demonstrated to be beneficial under fluctuating environments. It is not known, however, if fluctuating selection alone can result in bistable dynamics. Using a stochastic model of simple feedback networks, we apply f...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3296359/ https://ncbi.nlm.nih.gov/pubmed/22252387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2011.98 |
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