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Interpretation of morphogen gradients by a synthetic bistable circuit

During development, cells gain positional information through the interpretation of dynamic morphogen gradients. A proposed mechanism for interpreting opposing morphogen gradients is mutual inhibition of downstream transcription factors, but isolating the role of this specific motif within a natural...

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Publicat a:Nat Commun
Autors principals: Grant, Paul K., Szep, Gregory, Patange, Om, Halatek, Jacob, Coppard, Valerie, Csikász-Nagy, Attila, Haseloff, Jim, Locke, James C. W., Dalchau, Neil, Phillips, Andrew
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7608687/
https://ncbi.nlm.nih.gov/pubmed/33139718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19098-w
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