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A Unifying Hypothesis for Familial and Sporadic Alzheimer's Disease
Alzheimer's disease (AD) is characterised by the aggregation of two quite different proteins, namely, amyloid-beta (Aβ), which forms extracellular plaques, and tau, the main component of cytoplasmic neurofibrillary tangles. The amyloid hypothesis proposes that Aβ plaques precede tangle formatio...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3296276/ https://ncbi.nlm.nih.gov/pubmed/22482080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/978742 |
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