A Unifying Hypothesis for Familial and Sporadic Alzheimer's Disease

Alzheimer's disease (AD) is characterised by the aggregation of two quite different proteins, namely, amyloid-beta (Aβ), which forms extracellular plaques, and tau, the main component of cytoplasmic neurofibrillary tangles. The amyloid hypothesis proposes that Aβ plaques precede tangle formatio...

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Bibliografiske detaljer
Main Authors: Proctor, Carole J., Gray, Douglas A.
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296276/
https://ncbi.nlm.nih.gov/pubmed/22482080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/978742
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