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GSK3 and p53 - is there a link in Alzheimer's disease?

BACKGROUND: Recent evidence suggests that glycogen synthase kinase-3β (GSK3β) is implicated in both sporadic and familial forms of Alzheimer's disease. The transcription factor, p53 also plays a role and has been linked to an increase in tau hyperphosphorylation although the effect is indirect....

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Bibliografiske detaljer
Main Authors: Proctor, Carole J, Gray, Douglas A
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831894/
https://ncbi.nlm.nih.gov/pubmed/20181016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-5-7
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