Unfolded p53 in the pathogenesis of Alzheimer's disease: is HIPK2 the link?

p53 transcriptional activity depends mainly on posttranslational modifications and protein/protein interaction. Another important mechanism that controls p53 function is its conformational stability since p53 is an intrinsically unstable protein. An altered conformational state of p53, independent f...

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Autors principals: Stanga, Serena, Lanni, Cristina, Govoni, Stefano, Uberti, Daniela, D'Orazi, Gabriella, Racchi, Marco
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2010
Matèries:
Review
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984604/
https://ncbi.nlm.nih.gov/pubmed/20876941
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