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HIF-1α antagonizes p53-mediated apoptosis by triggering HIPK2 degradation

Many human diseases are characterized by the development of tissue hypoxia. Hypoxia-inducible factor (HIF) is a transcription factor that regulates fundamental cellular processes in response to changes in oxygen concentration, such as angiogenesis, survival, and alterations in metabolism. The levels...

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Detalhes bibliográficos
Main Authors: Nardinocchi, Lavinia, Puca, Rosa, D'Orazi, Gabriella
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047137/
https://ncbi.nlm.nih.gov/pubmed/21248371
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