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On the Pleiotropic Structure of the Genotype–Phenotype Map and the Evolvability of Complex Organisms

Analyses of effects of mutants on many traits have enabled estimates to be obtained of the magnitude of pleiotropy, and in reviews of such data others have concluded that the degree of pleiotropy is highly restricted, with implications on the evolvability of complex organisms. We show that these con...

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Библиографические подробности
Главные авторы: Hill, William G., Zhang, Xu-Sheng
Формат: Artigo
Язык:Inglês
Опубликовано: Genetics Society of America 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296247/
https://ncbi.nlm.nih.gov/pubmed/22214609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.135681
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