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On the Pleiotropic Structure of the Genotype–Phenotype Map and the Evolvability of Complex Organisms

Analyses of effects of mutants on many traits have enabled estimates to be obtained of the magnitude of pleiotropy, and in reviews of such data others have concluded that the degree of pleiotropy is highly restricted, with implications on the evolvability of complex organisms. We show that these con...

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Détails bibliographiques
Auteurs principaux: Hill, William G., Zhang, Xu-Sheng
Format: Artigo
Langue:Inglês
Publié: Genetics Society of America 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296247/
https://ncbi.nlm.nih.gov/pubmed/22214609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.135681
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