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On the Pleiotropic Structure of the Genotype–Phenotype Map and the Evolvability of Complex Organisms

Analyses of effects of mutants on many traits have enabled estimates to be obtained of the magnitude of pleiotropy, and in reviews of such data others have concluded that the degree of pleiotropy is highly restricted, with implications on the evolvability of complex organisms. We show that these con...

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Detalhes bibliográficos
Main Authors: Hill, William G., Zhang, Xu-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296247/
https://ncbi.nlm.nih.gov/pubmed/22214609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.135681
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