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On the Pleiotropic Structure of the Genotype–Phenotype Map and the Evolvability of Complex Organisms

Analyses of effects of mutants on many traits have enabled estimates to be obtained of the magnitude of pleiotropy, and in reviews of such data others have concluded that the degree of pleiotropy is highly restricted, with implications on the evolvability of complex organisms. We show that these con...

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Autors principals: Hill, William G., Zhang, Xu-Sheng
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296247/
https://ncbi.nlm.nih.gov/pubmed/22214609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.135681
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