Nanoscale Organization of Junctophilin-2 and Ryanodine Receptors within Peripheral Couplings of Rat Ventricular Cardiomyocytes

The peripheral distributions of the cardiac ryanodine receptor (RyR) and a junctional protein, junctophilin-2 (JPH2), were examined using single fluorophore localization-based super-resolution microscopy in rat ventricular myocytes. JPH2 was strongly associated with RyR clusters. Estimates of the co...

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Hlavní autoři: Jayasinghe, Isuru D., Baddeley, David, Kong, Cherrie H.T., Wehrens, Xander H.T., Cannell, Mark B., Soeller, Christian
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2012
Témata:
Biophysical Letters
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296050/
https://ncbi.nlm.nih.gov/pubmed/22404946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.01.034
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