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Optical single-channel resolution imaging of the ryanodine receptor distribution in rat cardiac myocytes

We have applied an optical super-resolution technique based on single-molecule localization to examine the peripheral distribution of a cardiac signaling protein, the ryanodine receptor (RyR), in rat ventricular myocytes. RyRs form clusters with a mean size of approximately 14 RyRs per cluster, whic...

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Main Authors: Baddeley, David, Jayasinghe, Isuru D., Lam, Leo, Rossberger, Sabrina, Cannell, Mark B., Soeller, Christian
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799702/
https://ncbi.nlm.nih.gov/pubmed/20018773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908971106
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